Selected Publications

Engineering of obligate intracellular bacteria: progress, challenges and paradigms. McClure EE, Chávez ASO, Shaw DK, Carlyon JA, Ganta RR, Noh SM, Wood DO, Bavoil PM, Brayton KA, Martinez JJ, McBride JW, Valdivia RH, Munderloh UG, Pedra JHF. Nature Reviews Microbiology, 2017 Jun 19. doi: 10.1038/nrmicro.2017.59. PMID:28626230.

Infection-derived lipids elicit an immune deficiency circuit in arthropods. Shaw DK, Wang X, Brown LJ, Chávez AS, Reif KE, Smith AA, Scott AJ, McClure EE, Boradia VM, Hammond HL, Sundberg EJ, Snyder GA, Liu L, DePonte K, Villar M, Ueti MW, de la Fuente J, Ernst RK, Pal U, Fikrig E, Pedra JH. Nature Communications 2017;8:14401. doi: 10.1038/ncomms14401. PMID:28195158.

The prostaglandin E2-EP3 receptor axis regulates Anaplasma phagocytophilum-mediated NLRC4 inflammasome activation. Wang X, Shaw DK, Hammond HL, Sutterwala FS, Rayamajhi M, Shirey KA, Perkins DJ, Bonventre JV, Velayutham TS, Evans SM, Rodino KG, VieBrock L, Scanlon KM, Carbonetti NH, Carlyon JA, Miao EA, McBride JW, Kotsyfakis M, Pedra JH. PLoS Pathog. 2016 Aug 2;12(8):e1005803.doi:10.1371/journal.ppat.1005803. PMID:27482714.

The tick protein sialostatin L2 binds to Annexin A2 and inhibits NLRC4-mediated inflammasome activation. Wang X, Shaw DK, Sakhon OS, Snyder GA, Sundberg EJ, Santambrogio L, Sutterwala FS, Dumler JS, Shirey KA, Perkins DJ, Richard K, Chagas AC, Calvo E, Kopecký J, Kotsyfakis M, Pedra JH. Infect Immun. 2016 May 24;84(6):1796-805. doi: 10.1128/IAI.01526-15.

Genomic insights into the parasitic vector of Lyme disease, Ixodes scapularis. Ixodes scapularis International Consortium. Nature Communications, 2016 7:10507 doi: 10.1038/ncomms10507.

Sialomes and mialomes: a systems biology view of tick interactions. Chmelař, Kotál J, Karim S, Kopacek P, Francischetti I, Pedra JHF, Kotsyfakis M. Trends in Parasitology, 2016 32: 242-254doi: 10.1016/j.pt.2015.10.002.

All for one and one for all on the tick-host battlefield. Chmelař  J, Kotál J, Kopecky J, Pedra JHF, Kotsyfakis M. Trends Parasitology, 2016 May;32(5):368-77. doi: 10.1016/j.pt.2016.01.004.

 

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